Genetic Predisposition to the Mortality in Septic Shock Patients: From GWAS to the Identification of a Regulatory Variant Modulating the Activity of a CISH Enhancer

The high mortality rate in septic shock patients is likely due to environmental and genetic factors, which influence the host response to infection. Two genome-wide association studies (GWAS) on 832 septic shock patients were performed. We used integrative bioinformatic approaches to annotate and pr...

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Detalles Bibliográficos
Autores principales: Rosier, Florian, Brisebarre, Audrey, Dupuis, Claire, Baaklini, Sabrina, Puthier, Denis, Brun, Christine, Pradel, Lydie C., Rihet, Pascal, Payen, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198806/
https://www.ncbi.nlm.nih.gov/pubmed/34072601
http://dx.doi.org/10.3390/ijms22115852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198806/
https://www.ncbi.nlm.nih.gov/pubmed/34072601
http://dx.doi.org/10.3390/ijms22115852

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