Structural Insights of Three 2,4-Disubstituted Dihydropyrimidine-5-carbonitriles as Potential Dihydrofolate Reductase Inhibitors

In this report, we describe the structural characterization of three 2,4-disubstituted-dihydropyrimidine-5-carbonitrile derivatives, namely 2-{[(4-nitrophenyl)methyl]sulfanyl}-6-oxo-4-propyl-1,6-dihydropyrimidine-5-carbonitrile 1, 4-(2-methylpropyl)-2-{[(4-nitrophenyl)methyl]sulfanyl}-6-oxo-1,6-dihy...

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Detalles Bibliográficos
Autores principales: Al-Wahaibi, Lamya H., Shaik, Althaf, Elmorsy, Mohammed A., Abdelbaky, Mohammed S. M., Garcia-Granda, Santiago, Thamotharan, Subbiah, Thiruvenkatam, Vijay, El-Emam, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198998/
https://www.ncbi.nlm.nih.gov/pubmed/34072467
http://dx.doi.org/10.3390/molecules26113286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8198998/
https://www.ncbi.nlm.nih.gov/pubmed/34072467
http://dx.doi.org/10.3390/molecules26113286

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