Cancer Cell Metabolism in Hypoxia: Role of HIF-1 as Key Regulator and Therapeutic Target

In order to meet the high energy demand, a metabolic reprogramming occurs in cancer cells. Its role is crucial in promoting tumor survival. Among the substrates in demand, oxygen is fundamental for bioenergetics. Nevertheless, tumor microenvironment is frequently characterized by low-oxygen conditio...

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Detalles Bibliográficos
Autores principales: Infantino, Vittoria, Santarsiero, Anna, Convertini, Paolo, Todisco, Simona, Iacobazzi, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199012/
https://www.ncbi.nlm.nih.gov/pubmed/34071836
http://dx.doi.org/10.3390/ijms22115703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199012/
https://www.ncbi.nlm.nih.gov/pubmed/34071836
http://dx.doi.org/10.3390/ijms22115703

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