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Functional Characterization of the Obesity-Linked Variant of the β(3)-Adrenergic Receptor

Adrenergic receptor β(3) (ADRβ(3)) is a member of the rhodopsin-like G protein-coupled receptor family. The binding of the ligand to ADRβ(3) activates adenylate cyclase and increases cAMP in the cells. ADRβ(3) is highly expressed in white and brown adipocytes and controls key regulatory pathways of...

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Detalles Bibliográficos
Autores principales: Haji, Esraa, Al Mahri, Saeed, Aloraij, Yumna, Malik, Shuja Shafi, Mohammad, Sameer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199065/
https://www.ncbi.nlm.nih.gov/pubmed/34072007
http://dx.doi.org/10.3390/ijms22115721