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Calpastatin-Mediated Inhibition of Calpain Ameliorates Skin Scar Formation after Burn Injury

Hypertrophic scars, the most common complication of burn injuries, are characterized by excessive deposition of fibroblast-derived extracellular matrix proteins. Calpain, a calcium-dependent protease, is involved in the fibroblast proliferation and extracellular matrix production observed in certain...

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Detalles Bibliográficos
Autores principales: Seo, Cheong Hoon, Cui, Hui Song, Kim, June-Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199077/
https://www.ncbi.nlm.nih.gov/pubmed/34071277
http://dx.doi.org/10.3390/ijms22115771