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Calpastatin-Mediated Inhibition of Calpain Ameliorates Skin Scar Formation after Burn Injury
Hypertrophic scars, the most common complication of burn injuries, are characterized by excessive deposition of fibroblast-derived extracellular matrix proteins. Calpain, a calcium-dependent protease, is involved in the fibroblast proliferation and extracellular matrix production observed in certain...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199077/ https://www.ncbi.nlm.nih.gov/pubmed/34071277 http://dx.doi.org/10.3390/ijms22115771 |