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Cyclovirobuxine D Induced-Mitophagy through the p65/BNIP3/LC3 Axis Potentiates Its Apoptosis-Inducing Effects in Lung Cancer Cells

Mitophagy plays a pro-survival or pro-death role that is cellular-context- and stress-condition-dependent. In this study, we revealed that cyclovirobuxine D (CVB-D), a natural compound derived from Buxus microphylla, was able to provoke mitophagy in lung cancer cells. CVB-D-induced mitophagy potenti...

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Detalles Bibliográficos
Autores principales: Zeng, Cheng, Zou, Tingting, Qu, Junyan, Chen, Xu, Zhang, Suping, Lin, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199090/
https://www.ncbi.nlm.nih.gov/pubmed/34072333
http://dx.doi.org/10.3390/ijms22115820