Cargando…
Cyclovirobuxine D Induced-Mitophagy through the p65/BNIP3/LC3 Axis Potentiates Its Apoptosis-Inducing Effects in Lung Cancer Cells
Mitophagy plays a pro-survival or pro-death role that is cellular-context- and stress-condition-dependent. In this study, we revealed that cyclovirobuxine D (CVB-D), a natural compound derived from Buxus microphylla, was able to provoke mitophagy in lung cancer cells. CVB-D-induced mitophagy potenti...
Autores principales: | Zeng, Cheng, Zou, Tingting, Qu, Junyan, Chen, Xu, Zhang, Suping, Lin, Zhenghong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199090/ https://www.ncbi.nlm.nih.gov/pubmed/34072333 http://dx.doi.org/10.3390/ijms22115820 |
Ejemplares similares
-
Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis
por: Choe, Sehyo Charley, et al.
Publicado: (2015) -
Aconitine induces cardiomyocyte damage by mitigating BNIP3‐dependent mitophagy and the TNFα‐NLRP3 signalling axis
por: Peng, Fu, et al.
Publicado: (2019) -
Melatonin inhibits NaIO(3)-induced ARPE-19 cell apoptosis via suppression of HIF-1α/BNIP3-LC3B/mitophagy signaling
por: Wang, Kai, et al.
Publicado: (2022) -
FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
por: Nguyen‐Dien, Giang Thanh, et al.
Publicado: (2023) -
BNIP3L/NIX regulates both mitophagy and pexophagy
por: Wilhelm, Léa P, et al.
Publicado: (2022)