Recombinant Long-Acting Thioredoxin Ameliorates AKI to CKD Transition via Modulating Renal Oxidative Stress and Inflammation

An effective strategy is highly desirable for preventing acute kidney injury (AKI) to chronic kidney disease (CKD) transition. Thioredoxin-1 (Trx), a redox-active protein that has anti-oxidative and anti-inflammatory properties, would be a candidate for this but its short half-life limits its clinic...

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Detalles Bibliográficos
Autores principales: Nishida, Kento, Watanabe, Hiroshi, Murata, Ryota, Tokumaru, Kai, Fujimura, Rui, Oshiro, Shun, Nagasaki, Taisei, Miyahisa, Masako, Hiramoto, Yuto, Nosaki, Hiroto, Imafuku, Tadashi, Maeda, Hitoshi, Fukagawa, Masafumi, Maruyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199127/
https://www.ncbi.nlm.nih.gov/pubmed/34070521
http://dx.doi.org/10.3390/ijms22115600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199127/
https://www.ncbi.nlm.nih.gov/pubmed/34070521
http://dx.doi.org/10.3390/ijms22115600

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