Melatonin Downregulates PD-L1 Expression and Modulates Tumor Immunity in KRAS-Mutant Non-Small Cell Lung Cancer

Non-small cell lung cancer (NSCLC) patients harboring a KRAS mutation have unfavorable therapeutic outcomes with chemotherapies, and the mutation also renders tolerance to immunotherapies. There is an unmet need for a new strategy for overcoming immunosuppression in KRAS-mutant NSCLC. The recently d...

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Detalles Bibliográficos
Autores principales: Chao, Yi-Chun, Lee, Kang-Yun, Wu, Sheng-Ming, Kuo, Deng-Yu, Shueng, Pei-Wei, Lin, Cheng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199131/
https://www.ncbi.nlm.nih.gov/pubmed/34073318
http://dx.doi.org/10.3390/ijms22115649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199131/
https://www.ncbi.nlm.nih.gov/pubmed/34073318
http://dx.doi.org/10.3390/ijms22115649

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