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Melatonin Downregulates PD-L1 Expression and Modulates Tumor Immunity in KRAS-Mutant Non-Small Cell Lung Cancer
Non-small cell lung cancer (NSCLC) patients harboring a KRAS mutation have unfavorable therapeutic outcomes with chemotherapies, and the mutation also renders tolerance to immunotherapies. There is an unmet need for a new strategy for overcoming immunosuppression in KRAS-mutant NSCLC. The recently d...
Autores principales: | Chao, Yi-Chun, Lee, Kang-Yun, Wu, Sheng-Ming, Kuo, Deng-Yu, Shueng, Pei-Wei, Lin, Cheng-Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199131/ https://www.ncbi.nlm.nih.gov/pubmed/34073318 http://dx.doi.org/10.3390/ijms22115649 |
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