Pharmacophore-Based Virtual Screening of Novel Competitive Inhibitors of the Neurodegenerative Disease Target Kynurenine-3-Monooxygenase

The pathogenesis of several neurodegenerative diseases such as Alzheimer’s or Huntington’s disease has been associated with metabolic dysfunctions caused by imbalances in the brain and cerebral spinal fluid levels of neuroactive metabolites. Kynurenine monooxygenase (KMO) is considered an ideal ther...

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Detalles Bibliográficos
Autores principales: Gotina, Lizaveta, Seo, Seon Hee, Kim, Chae Won, Lim, Sang Min, Pae, Ae Nim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199213/
https://www.ncbi.nlm.nih.gov/pubmed/34073016
http://dx.doi.org/10.3390/molecules26113314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199213/
https://www.ncbi.nlm.nih.gov/pubmed/34073016
http://dx.doi.org/10.3390/molecules26113314

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