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5-HT(1A) Serotonergic, α-Adrenergic and Opioidergic Receptors Mediate the Analgesic Efficacy of Vortioxetine in Mice

Vortioxetine is a multimodal antidepressant drug that affects several brain neurochemicals and has the potential to induce various pharmacological effects on the central nervous system. Therefore, we investigated the centrally mediated analgesic efficacy of this drug and the mechanisms underlying th...

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Detalles Bibliográficos
Autores principales: Turan Yücel, Nazlı, Kandemir, Ümmühan, Demir Özkay, Ümide, Can, Özgür Devrim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199248/
https://www.ncbi.nlm.nih.gov/pubmed/34071269
http://dx.doi.org/10.3390/molecules26113242