Inferring Single-Cell 3D Chromosomal Structures Based on the Lennard-Jones Potential

Reconstructing three-dimensional (3D) chromosomal structures based on single-cell Hi-C data is a challenging scientific problem due to the extreme sparseness of the single-cell Hi-C data. In this research, we used the Lennard-Jones potential to reconstruct both 500 kb and high-resolution 50 kb chrom...

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Detalles Bibliográficos
Autores principales: Zha, Mengsheng, Wang, Nan, Zhang, Chaoyang, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199262/
https://www.ncbi.nlm.nih.gov/pubmed/34072879
http://dx.doi.org/10.3390/ijms22115914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199262/
https://www.ncbi.nlm.nih.gov/pubmed/34072879
http://dx.doi.org/10.3390/ijms22115914

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