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Inferring Single-Cell 3D Chromosomal Structures Based on the Lennard-Jones Potential
Reconstructing three-dimensional (3D) chromosomal structures based on single-cell Hi-C data is a challenging scientific problem due to the extreme sparseness of the single-cell Hi-C data. In this research, we used the Lennard-Jones potential to reconstruct both 500 kb and high-resolution 50 kb chrom...
Autores principales: | Zha, Mengsheng, Wang, Nan, Zhang, Chaoyang, Wang, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199262/ https://www.ncbi.nlm.nih.gov/pubmed/34072879 http://dx.doi.org/10.3390/ijms22115914 |
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