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Opa1 Deficiency Promotes Development of Retinal Vascular Lesions in Diabetic Retinopathy

This study investigates whether reduced optic atrophy 1 (Opa1) level promotes apoptosis and retinal vascular lesions associated with diabetic retinopathy (DR). Four groups of mice: wild type (WT) control mice, streptozotocin (STZ)-induced diabetic mice, Opa1(+/−) mice, and diabetic Opa1(+/−) mice we...

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Detalles Bibliográficos
Autores principales: Kim, Dongjoon, Votruba, Marcela, Roy, Sayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199305/
https://www.ncbi.nlm.nih.gov/pubmed/34072974
http://dx.doi.org/10.3390/ijms22115928