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Widespread Exaptation of L1 Transposons for Transcription Factor Binding in Breast Cancer

L1 transposons occupy 17% of the human genome and are widely exapted for the regulation of human genes, particularly in breast cancer, where we have previously shown abundant cancer-specific transcription factor (TF) binding sites within the L1PA2 subfamily. In the current study, we performed a comp...

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Detalles Bibliográficos
Autores principales: Jiang, Jiayue-Clara, Rothnagel, Joseph A., Upton, Kyle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199441/
https://www.ncbi.nlm.nih.gov/pubmed/34070697
http://dx.doi.org/10.3390/ijms22115625