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Widespread Exaptation of L1 Transposons for Transcription Factor Binding in Breast Cancer
L1 transposons occupy 17% of the human genome and are widely exapted for the regulation of human genes, particularly in breast cancer, where we have previously shown abundant cancer-specific transcription factor (TF) binding sites within the L1PA2 subfamily. In the current study, we performed a comp...
Autores principales: | Jiang, Jiayue-Clara, Rothnagel, Joseph A., Upton, Kyle R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199441/ https://www.ncbi.nlm.nih.gov/pubmed/34070697 http://dx.doi.org/10.3390/ijms22115625 |
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