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Molecular Elucidation of a Urate Oxidase from Deinococcus radiodurans for Hyperuricemia and Gout Therapy

Urate oxidase initiates the uric acid degradation pathways and is extensively used for protein drug development for gout therapy and serum uric acid diagnosis. We first present the biochemical and structural elucidation of a urate oxidase from the extremophile microorganism Deinococcus radiodurans (...

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Detalles Bibliográficos
Autores principales: Chiu, Yi-Chih, Hsu, Ting-Syuan, Huang, Chen-Yu, Hsu, Chun-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199477/
https://www.ncbi.nlm.nih.gov/pubmed/34070642
http://dx.doi.org/10.3390/ijms22115611