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Molecular Elucidation of a Urate Oxidase from Deinococcus radiodurans for Hyperuricemia and Gout Therapy
Urate oxidase initiates the uric acid degradation pathways and is extensively used for protein drug development for gout therapy and serum uric acid diagnosis. We first present the biochemical and structural elucidation of a urate oxidase from the extremophile microorganism Deinococcus radiodurans (...
Autores principales: | Chiu, Yi-Chih, Hsu, Ting-Syuan, Huang, Chen-Yu, Hsu, Chun-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199477/ https://www.ncbi.nlm.nih.gov/pubmed/34070642 http://dx.doi.org/10.3390/ijms22115611 |
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