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Novel Bis- and Mono-Pyrrolo[2,3-d]pyrimidine and Purine Derivatives: Synthesis, Computational Analysis and Antiproliferative Evaluation

Novel symmetrical bis-pyrrolo[2,3-d]pyrimidines and bis-purines and their monomers were synthesized and evaluated for their antiproliferative activity in human lung adenocarcinoma (A549), cervical carcinoma (HeLa), ductal pancreatic adenocarcinoma (CFPAC-1) and metastatic colorectal adenocarcinoma (...

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Detalles Bibliográficos
Autores principales: Bistrović Popov, Andrea, Vianelo, Robert, Grbčić, Petra, Sedić, Mirela, Pavelić, Sandra Kraljević, Pavelić, Krešimir, Raić-Malić, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199500/
https://www.ncbi.nlm.nih.gov/pubmed/34206076
http://dx.doi.org/10.3390/molecules26113334