An Unbalanced Synaptic Transmission: Cause or Consequence of the Amyloid Oligomers Neurotoxicity?

Amyloid-β (Aβ) 1-40 and 1-42 peptides are key mediators of synaptic and cognitive dysfunction in Alzheimer’s disease (AD). Whereas in AD, Aβ is found to act as a pro-epileptogenic factor even before plaque formation, amyloid pathology has been detected among patients with epilepsy with increased ris...

Descripción completa

Detalles Bibliográficos
Autores principales: Sciaccaluga, Miriam, Megaro, Alfredo, Bellomo, Giovanni, Ruffolo, Gabriele, Romoli, Michele, Palma, Eleonora, Costa, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199544/
https://www.ncbi.nlm.nih.gov/pubmed/34206089
http://dx.doi.org/10.3390/ijms22115991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199544/
https://www.ncbi.nlm.nih.gov/pubmed/34206089
http://dx.doi.org/10.3390/ijms22115991

Ejemplares similares