The Catecholaldehyde Hypothesis for the Pathogenesis of Catecholaminergic Neurodegeneration: What We Know and What We Do Not Know

3,4-Dihydroxyphenylacetaldehyde (DOPAL) is the focus of the catecholaldehyde hypothesis for the pathogenesis of Parkinson’s disease and other Lewy body diseases. The catecholaldehyde is produced via oxidative deamination catalyzed by monoamine oxidase (MAO) acting on cytoplasmic dopamine. DOPAL is a...

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Detalles Bibliográficos
Autor principal: Goldstein, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199574/
https://www.ncbi.nlm.nih.gov/pubmed/34206133
http://dx.doi.org/10.3390/ijms22115999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199574/
https://www.ncbi.nlm.nih.gov/pubmed/34206133
http://dx.doi.org/10.3390/ijms22115999

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