Augmented Chondroitin Sulfate Proteoglycan Has Therapeutic Potential for Intervertebral Disc Degeneration by Stimulating Anabolic Turnover in Bovine Nucleus Pulposus Cells under Changes in Hydrostatic Pressure

Nucleus pulposus (NP) cells are exposed to changes in hydrostatic pressure (HP) and osmotic pressure within the intervertebral disc. We focused on main disc matrix components, chondroitin sulfate proteoglycan (CSPG) and hyaluronan (HA) to elucidate the capability of augmented CSPG to enhance the ana...

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Detalles Bibliográficos
Autores principales: Takeoka, Yoshiki, Paladugu, Phani, Kang, James D., Mizuno, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199579/
https://www.ncbi.nlm.nih.gov/pubmed/34199496
http://dx.doi.org/10.3390/ijms22116015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199579/
https://www.ncbi.nlm.nih.gov/pubmed/34199496
http://dx.doi.org/10.3390/ijms22116015

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