Synthesis and Antinociceptive Effect of Some Thiazole-Piperazine Derivatives: Involvement of Opioidergic System in the Activity

In this study, we aimed to design and synthesize novel molecules carrying both the thiazole and piperazine rings in their structures and to investigate their antinociceptive activity. Targeted compounds were obtained by reacting thiosemicarbazide derivative and appropriate 2-bromoacetophenone in eth...

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Detalles Bibliográficos
Autores principales: Yücel, Nazlı Turan, Osmaniye, Derya, Kandemir, Ümmühan, Evren, Asaf Evrim, Can, Özgür Devrim, Demir Özkay, Ümide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199615/
https://www.ncbi.nlm.nih.gov/pubmed/34199486
http://dx.doi.org/10.3390/molecules26113350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199615/
https://www.ncbi.nlm.nih.gov/pubmed/34199486
http://dx.doi.org/10.3390/molecules26113350

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