DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat

As we age, our bodies accrue damage in the form of DNA mutations. These mutations lead to the generation of sub-optimal proteins, resulting in inadequate cellular homeostasis and senescence. The build-up of senescent cells negatively affects the local cellular micro-environment and drives ageing ass...

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Detalles Bibliográficos
Autores principales: Boughey, Harvey, Jurga, Mateusz, El-Khamisy, Sherif F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199619/
https://www.ncbi.nlm.nih.gov/pubmed/34199458
http://dx.doi.org/10.3390/ijms22116011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199619/
https://www.ncbi.nlm.nih.gov/pubmed/34199458
http://dx.doi.org/10.3390/ijms22116011

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