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HGF/c-Met Inhibition as Adjuvant Therapy Improves Outcomes in an Orthotopic Mouse Model of Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer (PC) has a poor prognosis. Even though surgical resection and adjuvant chemotherapy is the most effective therapy, recurrence remains common. In this paper, we investigate the effectiveness of dual inhibition of hepatocyte growth factor (HGF) and c-MET when used as...

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Detalles Bibliográficos
Autores principales: Pang, Tony C. Y., Xu, Zhihong, Mekapogu, Alpha Raj, Pothula, Srinivasa, Becker, Therese, Corley, Susan, Wilkins, Marc R., Goldstein, David, Pirola, Romano, Wilson, Jeremy, Apte, Minoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199621/
https://www.ncbi.nlm.nih.gov/pubmed/34199452
http://dx.doi.org/10.3390/cancers13112763