Structural and Energetic Affinity of Annocatacin B with ND1 Subunit of the Human Mitochondrial Respiratory Complex I as a Potential Inhibitor: An In Silico Comparison Study with the Known Inhibitor Rotenone

ND1 subunit possesses the majority of the inhibitor binding domain of the human mitochondrial respiratory complex I. This is an attractive target for the search for new inhibitors that seek mitochondrial dysfunction. It is known, from in vitro experiments, that some metabolites from Annona muricata...

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Detalles Bibliográficos
Autores principales: Febres-Molina, Camilo, Aguilar-Pineda, Jorge A., Gamero-Begazo, Pamela L., Barazorda-Ccahuana, Haruna L., Valencia, Diego E., Vera-López, Karin J., Davila-Del-Carpio, Gonzalo, Gómez, Badhin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199665/
https://www.ncbi.nlm.nih.gov/pubmed/34199390
http://dx.doi.org/10.3390/polym13111840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199665/
https://www.ncbi.nlm.nih.gov/pubmed/34199390
http://dx.doi.org/10.3390/polym13111840

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