Protein Aggregation Landscape in Neurodegenerative Diseases: Clinical Relevance and Future Applications

Intrinsic disorder is a natural feature of polypeptide chains, resulting in the lack of a defined three-dimensional structure. Conformational changes in intrinsically disordered regions of a protein lead to unstable β-sheet enriched intermediates, which are stabilized by intermolecular interactions...

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Detalles Bibliográficos
Autores principales: Candelise, Niccolò, Scaricamazza, Silvia, Salvatori, Illari, Ferri, Alberto, Valle, Cristiana, Manganelli, Valeria, Garofalo, Tina, Sorice, Maurizio, Misasi, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199687/
https://www.ncbi.nlm.nih.gov/pubmed/34199513
http://dx.doi.org/10.3390/ijms22116016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199687/
https://www.ncbi.nlm.nih.gov/pubmed/34199513
http://dx.doi.org/10.3390/ijms22116016

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