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The physiological role of Homer2a and its novel short isoform, Homer2e, in NMDA receptor-mediated apoptosis in cerebellar granule cells

Homer is a postsynaptic scaffold protein, which has long and short isoforms. The long form of Homer consists of an N-terminal target-binding domain and a C-terminal multimerization domain, linking multiple proteins within a complex. The short form of Homer only has the N-terminal domain and likely a...

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Detalles Bibliográficos
Autores principales: Furuichi, Teiichi, Muto, Yuko, Sadakata, Tetsushi, Sato, Yumi, Hayashi, Kanehiro, Shiraishi-Yamaguchi, Yoko, Shinoda, Yo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199691/
https://www.ncbi.nlm.nih.gov/pubmed/34118975
http://dx.doi.org/10.1186/s13041-021-00804-8