mTOR Driven Gene Transcription Is Required for Cholesterol Production in Neurons of the Developing Cerebral Cortex

Dysregulated mammalian target of rapamycin (mTOR) activity is associated with various neurodevelopmental disorders ranging from idiopathic autism spectrum disorders (ASD) to syndromes caused by single gene defects. This suggests that maintaining mTOR activity levels in a physiological range is essen...

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Detalles Bibliográficos
Autores principales: Schüle, Martin, Butto, Tamer, Dewi, Sri, Schlichtholz, Laura, Strand, Susanne, Gerber, Susanne, Endres, Kristina, Schweiger, Susann, Winter, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199781/
https://www.ncbi.nlm.nih.gov/pubmed/34204880
http://dx.doi.org/10.3390/ijms22116034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199781/
https://www.ncbi.nlm.nih.gov/pubmed/34204880
http://dx.doi.org/10.3390/ijms22116034

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