Towards Profiling of the G-Quadruplex Targeting Drugs in the Living Human Cells Using NMR Spectroscopy

Recently, the (1)H-detected in-cell NMR spectroscopy has emerged as a unique tool allowing the characterization of interactions between nucleic acid-based targets and drug-like molecules in living human cells. Here, we assess the application potential of (1)H and (19)F-detected in-cell NMR spectrosc...

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Detalles Bibliográficos
Autores principales: Krafčík, Daniel, Ištvánková, Eva, Džatko, Šimon, Víšková, Pavlína, Foldynová-Trantírková, Silvie, Trantírek, Lukáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199861/
https://www.ncbi.nlm.nih.gov/pubmed/34205000
http://dx.doi.org/10.3390/ijms22116042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199861/
https://www.ncbi.nlm.nih.gov/pubmed/34205000
http://dx.doi.org/10.3390/ijms22116042

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