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Identifying Cancer Drivers Using DRIVE: A Feature-Based Machine Learning Model for a Pan-Cancer Assessment of Somatic Missense Mutations

SIMPLE SUMMARY: Genes dictate the grounds of life by comprising molecular bases which encode proteins. A mutation represents a gene modification that may influence the protein function. Cancer occurs when the mutation triggers uncontrolled cellular growth. Judging by the cancer expansion, mutations...

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Detalles Bibliográficos
Autores principales: Dragomir, Ionut, Akbar, Adnan, Cassidy, John W., Patel, Nirmesh, Clifford, Harry W., Contino, Gianmarco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199862/
https://www.ncbi.nlm.nih.gov/pubmed/34205004
http://dx.doi.org/10.3390/cancers13112779