Anti-Cancer Activities of Thyrointegrin α(v)β(3) Antagonist Mono- and Bis-Triazole Tetraiodothyroacetic Acid Conjugated via Polyethylene Glycols in Glioblastoma

SIMPLE SUMMARY: Different Triazole Tetrac (TAT) thyrointegrin αvβ3 antagonists exhibited optimal therapeutic efficacy against U87 or primary glioblastoma cells. TAT containing molecules bind with high affinity to the integrin αvβ3 and plasma protein Transthyretin (TTR), which facilitate transport ac...

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Detalles Bibliográficos
Autores principales: Godugu, Kavitha, Rajabi, Mehdi, Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199894/
https://www.ncbi.nlm.nih.gov/pubmed/34204997
http://dx.doi.org/10.3390/cancers13112780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199894/
https://www.ncbi.nlm.nih.gov/pubmed/34204997
http://dx.doi.org/10.3390/cancers13112780

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