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Patterns and Prevalence of BRCA1 and BRCA2 Germline Mutations Among Patients with Triple-Negative Breast Cancer: Regional Perspectives

BACKGROUND: Among all subtypes, patients with triple-negative (TN) breast cancer is known for their poor outcome and their higher risk of harboring BRCA1 or BRCA2 pathogenic mutations. Identification of such mutations has clinical impact on breast and ovarian cancer prevention and treatment decision...

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Detalles Bibliográficos
Autores principales: Abdel-Razeq, Hikmat, Tamimi, Faris, Abujamous, Lama, Edaily, Sara, Abunasser, Mahmoud, Bater, Rayan, Salama, Osama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200144/
https://www.ncbi.nlm.nih.gov/pubmed/34135636
http://dx.doi.org/10.2147/CMAR.S316470