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An Overview of the Recent Development of Anticancer Agents Targeting the HIF-1 Transcription Factor

SIMPLE SUMMARY: As hypoxia-inducible factor 1 (HIF-1) is recognized as a target for cancer therapy, extensive efforts have been devoted to developing its inhibitors. We provide an overview of the latest information about basic, translational, and clinical research for the development of HIF-1 inhibi...

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Detalles Bibliográficos
Autores principales: Shirai, Yukari, Chow, Christalle C. T., Kambe, Gouki, Suwa, Tatsuya, Kobayashi, Minoru, Takahashi, Itsuki, Harada, Hiroshi, Nam, Jin-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200185/
https://www.ncbi.nlm.nih.gov/pubmed/34200019
http://dx.doi.org/10.3390/cancers13112813