Connectivity Map Analysis Indicates PI3K/Akt/mTOR Inhibitors as Potential Anti-Hypoxia Drugs in Neuroblastoma

SIMPLE SUMMARY: A large percentage of patients with neuroblastoma relapse and die, despite treatment, thus demanding new personalized strategies and therapeutic targets. Hypoxia, a condition of reduced oxygenation in several solid tumors, has profound effects on the neuroblastoma (NB) tumor biology...

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Detalles Bibliográficos
Autores principales: Uva, Paolo, Bosco, Maria Carla, Eva, Alessandra, Conte, Massimo, Garaventa, Alberto, Amoroso, Loredana, Cangelosi, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200206/
https://www.ncbi.nlm.nih.gov/pubmed/34199959
http://dx.doi.org/10.3390/cancers13112809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200206/
https://www.ncbi.nlm.nih.gov/pubmed/34199959
http://dx.doi.org/10.3390/cancers13112809

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