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Connectivity Map Analysis Indicates PI3K/Akt/mTOR Inhibitors as Potential Anti-Hypoxia Drugs in Neuroblastoma

SIMPLE SUMMARY: A large percentage of patients with neuroblastoma relapse and die, despite treatment, thus demanding new personalized strategies and therapeutic targets. Hypoxia, a condition of reduced oxygenation in several solid tumors, has profound effects on the neuroblastoma (NB) tumor biology...

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Detalles Bibliográficos
Autores principales:	Uva, Paolo, Bosco, Maria Carla, Eva, Alessandra, Conte, Massimo, Garaventa, Alberto, Amoroso, Loredana, Cangelosi, Davide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200206/ https://www.ncbi.nlm.nih.gov/pubmed/34199959 http://dx.doi.org/10.3390/cancers13112809

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