New Oxaliplatin-Pyrophosphato Analogs with Improved In Vitro Cytotoxicity

Two new Pt(II)-pyrophosphato complexes containing the carrier ligands cis-1,3-diaminocyclohexane (cis-1,3-DACH) and trans-1,2-diamine-4-cyclohexene (1,2-DACHEX), variants of the 1R,2R-diaminocyclohexane ligand present in the clinically used Pt-drug oxaliplatin, have been synthesized with the aim of...

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Detalles Bibliográficos
Autores principales: Barbanente, Alessandra, Iacobazzi, Rosa Maria, Azzariti, Amalia, Hoeschele, James D., Denora, Nunzio, Papadia, Paride, Pacifico, Concetta, Natile, Giovanni, Margiotta, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200237/
https://www.ncbi.nlm.nih.gov/pubmed/34200051
http://dx.doi.org/10.3390/molecules26113417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200237/
https://www.ncbi.nlm.nih.gov/pubmed/34200051
http://dx.doi.org/10.3390/molecules26113417

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