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Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting

BACKGROUND: Skeletal muscle wasting (SMW) in cancer patients is associated with increased morbidity, mortality, treatment intolerance and discontinuation, and poor quality of life. This is particularly true for patients with pancreatic ductal adenocarcinoma (PDAC), as over 85% experience SMW, which...

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Detalles Bibliográficos
Autores principales: Cole, Calvin L., Bachman, John F., Ye, Jian, Murphy, Joseph, Gerber, Scott A., Beck, Christopher A., Boyce, Brendan F., Muthukrishnan, Gowrishankar, Chakkalakal, Joe V., Schwarz, Edward M., Linehan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200439/
https://www.ncbi.nlm.nih.gov/pubmed/33960737
http://dx.doi.org/10.1002/jcsm.12699