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Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting
BACKGROUND: Skeletal muscle wasting (SMW) in cancer patients is associated with increased morbidity, mortality, treatment intolerance and discontinuation, and poor quality of life. This is particularly true for patients with pancreatic ductal adenocarcinoma (PDAC), as over 85% experience SMW, which...
Autores principales: | Cole, Calvin L., Bachman, John F., Ye, Jian, Murphy, Joseph, Gerber, Scott A., Beck, Christopher A., Boyce, Brendan F., Muthukrishnan, Gowrishankar, Chakkalakal, Joe V., Schwarz, Edward M., Linehan, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200439/ https://www.ncbi.nlm.nih.gov/pubmed/33960737 http://dx.doi.org/10.1002/jcsm.12699 |
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