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Palmitic Acid, but Not Lauric Acid, Induces Metabolic Inflammation, Mitochondrial Fragmentation, and a Drop in Mitochondrial Membrane Potential in Human Primary Myotubes

The chain length of saturated fatty acids may dictate their impact on inflammation and mitochondrial dysfunction, two pivotal players in the pathogenesis of insulin resistance. However, these paradigms have only been investigated in animal models and cell lines so far. Thus, the aim of this study wa...

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Detalles Bibliográficos
Autores principales: Sergi, Domenico, Luscombe-Marsh, Natalie, Naumovski, Nenad, Abeywardena, Mahinda, O'Callaghan, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200524/
https://www.ncbi.nlm.nih.gov/pubmed/34136519
http://dx.doi.org/10.3389/fnut.2021.663838