Inhibition of miR-200b-3p alleviates lipid accumulation and promotes cholesterol efflux by targeting ABCA1 in macrophage-derived foam cells

Atherosclerosis (As) is a chronic cardiovascular disease characterized by abnormal of lipid accumulation and cholesterol efflux. The present study aimed to investigate whether the micro-RNA (miR)-200b-3p could exacerbate As by promoting lipid accumulation and inhibiting cholesterol efflux via ATP-bi...

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Detalles Bibliográficos
Autores principales: Wu, Yu-Ting, Li, Jiang-Bin, Lin, Hui-Qin, Zhang, Guo-Xin, Hong, Cong-Min, Li, Ming, Guo, Zhi-Jun, Yang, Yan-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200800/
https://www.ncbi.nlm.nih.gov/pubmed/34149877
http://dx.doi.org/10.3892/etm.2021.10263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200800/
https://www.ncbi.nlm.nih.gov/pubmed/34149877
http://dx.doi.org/10.3892/etm.2021.10263

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