SPECT/CT Imaging, Biodistribution and Radiation Dosimetry of a (177)Lu-DOTA-Integrin αvβ6 Cystine Knot Peptide in a Pancreatic Cancer Xenograft Model

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant neoplasms, as many cases go undetected until they reach an advanced stage. Integrin αvβ6 is a cell surface receptor overexpressed in PDAC. Consequently, it may serve as a target for the development of probe...

Descripción completa

Detalles Bibliográficos
Autores principales: Sachindra, Sachindra, Hellberg, Teresa, Exner, Samantha, Prasad, Sonal, Beindorff, Nicola, Rogalla, Stephan, Kimura, Richard, Gambhir, Sanjiv Sam, Wiedenmann, Bertram, Grötzinger, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200818/
https://www.ncbi.nlm.nih.gov/pubmed/34136410
http://dx.doi.org/10.3389/fonc.2021.684713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200818/
https://www.ncbi.nlm.nih.gov/pubmed/34136410
http://dx.doi.org/10.3389/fonc.2021.684713

Ejemplares similares