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SPECT/CT Imaging, Biodistribution and Radiation Dosimetry of a (177)Lu-DOTA-Integrin αvβ6 Cystine Knot Peptide in a Pancreatic Cancer Xenograft Model

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant neoplasms, as many cases go undetected until they reach an advanced stage. Integrin αvβ6 is a cell surface receptor overexpressed in PDAC. Consequently, it may serve as a target for the development of probe...

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Detalles Bibliográficos
Autores principales:	Sachindra, Sachindra, Hellberg, Teresa, Exner, Samantha, Prasad, Sonal, Beindorff, Nicola, Rogalla, Stephan, Kimura, Richard, Gambhir, Sanjiv Sam, Wiedenmann, Bertram, Grötzinger, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200818/ https://www.ncbi.nlm.nih.gov/pubmed/34136410 http://dx.doi.org/10.3389/fonc.2021.684713

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