Design, Synthesis, Biological Evaluation and Silico Prediction of Novel Sinomenine Derivatives

Sinomenine is a morphinan alkaloid with a variety of biological activities. Its derivatives have shown significant cytotoxic activity against different cancer cell lines in many studies. In this study, two series of sinomenine derivatives were designed and synthesized by modifying the active positio...

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Detalles Bibliográficos
Autores principales: Li, Shoujie, Gao, Mingjie, Nian, Xin, Zhang, Liyu, Li, Jinjie, Cui, Dongmei, Zhang, Chen, Zhao, Changqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200971/
https://www.ncbi.nlm.nih.gov/pubmed/34200341
http://dx.doi.org/10.3390/molecules26113466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200971/
https://www.ncbi.nlm.nih.gov/pubmed/34200341
http://dx.doi.org/10.3390/molecules26113466

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