The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity

In nonalcoholic steatohepatitis animal models, an increased lipid droplet size in hepatocytes is associated with fibrogenesis. Hepatocytes with large droplet (Ld-MaS) or small droplet (Sd-MaS) macrovesicular steatosis may coexist in the human liver, but the factors associated with the predominance o...

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Detalles Bibliográficos
Autores principales: Ferri, Flaminia, Carotti, Simone, Carpino, Guido, Mischitelli, Monica, Cantafora, Alfredo, Molinaro, Antonio, Argenziano, Maria Eva, Parisse, Simona, Corsi, Alessandro, Riminucci, Mara, Lai, Quirino, Mennini, Gianluca, Spadetta, Gustavo, Pugliese, Francesco, Rossi, Massimo, Morini, Sergio, Gaudio, Eugenio, Ginanni Corradini, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200978/
https://www.ncbi.nlm.nih.gov/pubmed/34198853
http://dx.doi.org/10.3390/ijms22116100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200978/
https://www.ncbi.nlm.nih.gov/pubmed/34198853
http://dx.doi.org/10.3390/ijms22116100

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