Aldosterone Negatively Regulates Nrf2 Activity: An Additional Mechanism Contributing to Oxidative Stress and Vascular Dysfunction by Aldosterone

High levels of aldosterone (Aldo) trigger oxidative stress and vascular dysfunction independent of effects on blood pressure. We sought to determine whether Aldo disrupts Nrf2 signaling, the main transcriptional factor involved in antioxidant responses that aggravate cell injury. Thoracic aorta from...

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Detalles Bibliográficos
Autores principales: Rodrigues, Daniel, Costa, Tiago J., Silva, Josiane F., Neto, José Teles de Oliveira, Alves, Juliano V., Fedoce, Aline G., Costa, Rafael Menezes, Tostes, Rita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201089/
https://www.ncbi.nlm.nih.gov/pubmed/34200377
http://dx.doi.org/10.3390/ijms22116154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201089/
https://www.ncbi.nlm.nih.gov/pubmed/34200377
http://dx.doi.org/10.3390/ijms22116154

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