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Safety Pharmacology Study of ET-26 Hydrochloride, a Potential Drug for Intravenous General Anesthesia, in Rats and Beagle Dogs

Background: ET-26 hydrochloride (ET-26HCl), a class 1 new drug, was developed to reserve the advantages of etomidate with a mild adrenocortical inhibition. Purpose: this study was to evaluate the potential adverse effects on the cardiovascular system of beagle dogs and the respiratory and central ne...

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Detalles Bibliográficos
Autores principales: Zhang, YuJun, Jiang, YingYing, Chang, Pan, Kang, Yi, Gong, DeYing, Liu, Jin, Zhang, WenSheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201096/
https://www.ncbi.nlm.nih.gov/pubmed/34135759
http://dx.doi.org/10.3389/fphar.2021.679381