Topical Astodrimer Sodium, a Non-Toxic Polyanionic Dendrimer, Demonstrates Antiviral Activity in an Experimental Ocular Adenovirus Infection Model

There is no approved antiviral therapy for adenovirus (HAdV) ocular infections. Astodrimer sodium (SPL7013) is a polyanionic dendrimer with antiviral activity. The current study evaluated the ocular tolerability and anti-adenoviral efficacy of topical SPL7013 in rabbit ocular models. In a tolerabili...

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Detalles Bibliográficos
Autores principales: Romanowski, Eric G., Yates, Kathleen A., Paull, Jeremy R. A., Heery, Graham P., Shanks, Robert M. Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201124/
https://www.ncbi.nlm.nih.gov/pubmed/34198721
http://dx.doi.org/10.3390/molecules26113419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201124/
https://www.ncbi.nlm.nih.gov/pubmed/34198721
http://dx.doi.org/10.3390/molecules26113419

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