Congenital Deletion of Nedd4-2 in Lung Epithelial Cells Causes Progressive Alveolitis and Pulmonary Fibrosis in Neonatal Mice

Recent studies found that expression of NEDD4-2 is reduced in lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and that the conditional deletion of Nedd4-2 in lung epithelial cells causes IPF-like disease in adult mice via multiple defects, including dysregulation of the epithelial...

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Detalles Bibliográficos
Autores principales: Leitz, Dominik H. W., Duerr, Julia, Mulugeta, Surafel, Seyhan Agircan, Ayça, Zimmermann, Stefan, Kawabe, Hiroshi, Dalpke, Alexander H., Beers, Michael F., Mall, Marcus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201155/
https://www.ncbi.nlm.nih.gov/pubmed/34200296
http://dx.doi.org/10.3390/ijms22116146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201155/
https://www.ncbi.nlm.nih.gov/pubmed/34200296
http://dx.doi.org/10.3390/ijms22116146

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